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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10142L | P-Ethynylphenylalanine hydrochloride | 4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base) | Hydroxylase |
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanine hydrochloride to inhibit selectively and reversibly the b... | |||
T1447 | Fenclonine | Fenchlonine,PCPA,CP-10188,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine | Hydroxylase |
Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine(CP-10188) acts pharmacologically to dep... | |||
T41143 | PCPA methyl ester hydrochloride | 4-Chloro-DL-phenylalanine methyl ester hydrochloride | 5-HT Receptor , Hydroxylase |
pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood... | |||
T10142 | P-Ethynylphenylalanine | 4-Ethynyl-L-phenylalanine | Others , Hydroxylase |
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM. | |||
T41274 | P-Fluoro-L-phenylalanine | Hydroxylase | |
p-Fluoro-L-phenylalanine is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli with an... | |||
T78228 | 4-Chloro-L-phenylalanine | L-4-Chlorophenylalanine,L-PCPA | 5-HT Receptor |
4-Chloro-L-phenylalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis.4-Chloro-L-phenylalanine is also a non-specific antagonist of tryptophan hydroxylase (TPH1 and TPH2). | |||
T21366 | Sapropterin free base | BPH4,Dapropterin,6R-BH4,Tetrahydro-6-biopterin,THB,Phenoptin | |
Sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of dopamine, epinephrine, melatoni... | |||
T36384 | DL-Tyrosine-13C9,15N | L-Tyrosine-13C9,15N | |
L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylal... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4781 | N-Acetyl-L-phenylalanine | N-Ac-Phenylalanine | Others , Endogenous Metabolite |
N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) is an essential amino acid produced for medical, feed, and nutritional applications. It appears in large amount in urine of patients with phenylketonuria which is a human gen... | |||
T7117 | Sapropterin dihydrochloride | Sapropterin Hydrochloride,6R-Tetrahydro-L-biopterin dihydrochloride,6R-BH4 dihydrochloride | Hydroxylase |
Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU. | |||
T5290 | (S)-2-Hydroxy-3-phenylpropanoic acid | L-(−)-3-Phenyllactic acid | Others , Endogenous Metabolite |
(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase. The ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02707 | PAH Protein, Human, Recombinant (415 Asn/Asp, His) | Human | Baculovirus Insect Cells |
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si... | |||
TMPJ-01043 | PHS Protein, Human, Recombinant (His) | Human | E. coli |
Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterin... |